see also my Profile on Google Scholar, ORCID, Scopus, or ResearchGate


  1. M. Kohl. Einführung in die statistische Datenanalyse mit R. 1. Auflage, 2015, 239 Seiten, kostenlos.
    ISBN: 978-87-403-1156-3.
    Einführung in die statistische Datenanalyse mit R
  2. M. Kohl. Introduction to statistical data analysis with R. 1st edition, 2015, 228 pages, free.
    ISBN: 978-87-403-1123-5.
    Introduction to statistical data analysis with R
  3. M. Kohl. Analyse von Genexpressionsdaten - mit R und Bioconductor. 1. Auflage, 2013, 197 Seiten, kostenlos.
    ISBN: 978-87-403-0349-0.
    Analyse von Genexpressionsdaten
  4. Dissertation: "Numerical Contributions to the Asymptotic Theory of Robustness" (2005) [14.9 MB]
    1. Referee and advisor: Prof. Dr. H. Rieder,
    2. Referee: Prof. Dr. S. Morgenthaler
    Official version under:


  1. W. Kemmler, M. Bebenek, M. Kohl, S. von Stengel.
    "Exercise and fractures in postmenopausal women. Final results of the controlled Erlangen Fitness and Osteoporosis Prevention Study (EFOPS).".
    Osteoporos Int. 2015 May 12. [Epub ahead of print]
  2. W. Kemmler, M. Bebenek, S. von Stengel, M. Kohl, J. Bauer.
    "Increases of Cardiometabolic Risk in Young Adults. Impact of Exercise Reductions during the College Years.".
    British Journal of Medicine & Medical Research 01/2015, 8(86):485-494.
  3. G.P. Otto, J. Hurtado-Oliveros, H.-Y. Chung, K. Knoll, T. Neumann, H.J. Müller, M. Herbsleb, M. Kohl, M. Busch, M. Sossdorf, R.A. Claus.
    "Plasma neutrophil gelatinase-associated lipocalin is primarily related to inflammation during sepsis: A translational approach.".
    PLoS One. 2015, 10(4):e0124429.
  4. W. Kemmler, M. Kohl, M. Bebenek, S. von Stengel.
    "Körperliche Belastung und kardiometabolisches Risiko bei jungen Erwachsenen.".
    Dtsch Z Sportmed. 2015, 66(4): 85-91.
  5. W. Kemmler, M. Kohl, M. Bebenek, S. von Stengel.
    "Entwicklung von Übergewicht und Adipositas im jungen Erwachsenenalter - Stellenwert berufsbedingter Veränderungen des Sporttreibens auf Fettmasse, fettfreie Masse und Körpermasse bei Studenten.".
    Wiener Medizinische Wochenschrift 2015, 165(5-6): 107-115.
  6. D. Pupashenko, P. Ruckdeschel, M. Kohl.
    "L_2 Differentiability of Generalized Linear Models".
    Statistics & Probability Letters 2015; 97: 155–164.
  7. M. Egert, K. Späth, K. Weik, H. Kunzelmann, C. Horn, M. Kohl, F. Blessing.
    "Bacteria on smartphone touchscreens in a German university setting and evaluation of two widely used cleaning methods.".
    Folia Microbiol (Praha) 2015; 60(2): 159-64.
  8. P. Ruckdeschel and M. Kohl (both authors contributed equally).
    "General Purpose Convolution Algorithm in S4-Classes by means of FFT".
    Journal of Statistical Software 2014; 59(4): 1–25.
  9. J.R. Perkins, A. Antunes-Martins, M. Calvo, J. Grist, W. Rust, R. Schmid, T. Hildebrandt, M. Kohl, C. Orengo, S.B. McMahon, D.L.H. Bennett.
    "A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat".
    Molecular Pain 2014, 10:7. Highly accessed
  10. M.W. Sieber, M. Guenther, N. Jaenisch, D. Albrecht-Eckhardt, M. Kohl, O.W. Witte, C. Frahm.
    "Age-specific transcriptional response to stroke".
    Neurobiology of Aging 2014 Jul; 35(7): 1744–1754.
  11. M. Sossdorf, G.P. Otto, K. Menge, R.A. Claus, W. Lösche, B. Kabisch, M. Kohl, U.C. Smolenski, P. Schlattmann, K. Reinhart, J. Winning.
    "Potential effect of physiotherapeutic treatment on mortality rate in patients with severe sepsis and septic shock: A retrospective cohort analysis".
    Crit Care 2013 Dec; 28(6):954–8.
  12. O. Bayer, D. Schwarzkopf, T. Doenst, D. Cook, B. Kabisch, C. Schelenz, M. Bauer, N.C. Riedemann, Y. Sakr, M. Kohl, K. Reinhart, C.S. Hartog.
    "Perioperative Fluid Therapy With Tetrastarch and Gelatin in Cardiac Surgery - A Prospective Sequential Analysis".
    Crit Care Med. 2013 Nov; 41(11):2532–42.
  13. F. Flessa, A. Kehl and M. Kohl.
    "Analysing diversity and community structures using PCR-RFLP: a new software application".
    Molecular Ecology Resources 2013 Jul; 13(4):726-33.
  14. K. Pöttgen und M. Kohl.
    "Propriozeption im Fußball".
    medical sports network 02.13: 34-37.
  15. M. Kohl.
    "Feature Selection in Statistical Classification".
    International Journal of Statistics in Medical Research 2012 Dec; 1(2):177-178.
  16. J. Perkins, N.I. Abdul Rahman, M. Kohl.
    "Analysis of RT-qPCR Data".
    International Journal of Statistics in Medical Research 2012 Dec; 1(2):174-176.
  17. M. Kohl.
    "Analysis of Microarray Data".
    International Journal of Statistics in Medical Research 2012 Sep; 1(1):82-83.
  18. M. Kohl.
    "Performance Measures in Binary Classification".
    International Journal of Statistics in Medical Research 2012 Sep; 1(1):79-81.
  19. U. Kern, V. Busch, R. Müller, M. Kohl, F. Birklein.
    "Phantom Limb Pain in Daily Practice—Still a Lot of Work to Do!".
    Pain Med 2012 Dec; 13(12):1611-26.
  20. O. Bayer, K. Reinhart, M. Kohl, B. Kabisch, J. Marshall, Y. Sakr, M. Bauer, C. Hartog, D. Schwarzkopf, N. Riedemann.
    "Effects of fluid resuscitation with synthetic colloids or crystalloids alone on shock reversal, fluid balance, and patient outcomes in patients with severe sepsis: A prospective sequential analysis*".
    Crit Care Med. 2012 Sep; 40(9):2543-2551.
  21. J. Perkins, J. Dawes, S. McMahon, D. Bennett, C. Orengo, M. Kohl.
    "ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data".
    BMC Genomics 2012, 13:296. Highly accessed
  22. M. Weber, S. Lambeck, N. Ding, S. Henken, M. Kohl, H.P. Deigner, D.P. Enot, E.I. Igwe, L. Frappart, M. Kiehntopf, R.A. Claus, T. Kamradt, D. Weih, Y. Vodovotz, D.E. Briles, A.D. Ogunniyi, J.C. Paton, U.A. Maus, M. Bauer.
    "Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia".
    FASEB J 2012 Jun; 26(6):2424-36.
  23. M. Kohl.
    "Bounded influence estimation for regression and scale".
    Statistics 2012; 46(4):473-488.
  24. U. Kern, M. Kohl, U. Seifert, T. Schlereth.
    "Effect of botulinum toxin type B on residual limb sweating and pain. Is there a chance for indirect phantom pain reduction by improved prosthesis use?".
    [Article in German]
    Schmerz 2012 Apr; 26(2):176-184.
  25. M. Kohl, S. Koch, M. Keller, H.P. Deigner.
    "Biochips: Bright Future in Clinical Dx?".
    Journal of Biochips and Tissue chips 2011, S1. Published October 29, 2011.
  26. U. Kern, M. Kohl, U. Seifert, T. Schlereth.
    "Botulinum Toxin Type B in the Treatment of Residual Limb Hyperhidrosis for Lower Limb Amputees: A Pilot Study".
    American Journal of Physical Medicine & Rehabilitation 2011 April;90(4):321-329.
  27. C.S. Hartog, M. Kohl, K. Reinhart.
    "A Systematic Review of Third-Generation Hydroxyethyl Starch (HES 130/0.4) in Resuscitation: Safety Not Adequately Addressed".
    Anesth Analg. 2011 Mar;112(3):635-45.
  28. O. Bayer, K. Reinhart, Y. Sakr, B. Kabisch, M. Kohl, N.C. Riedemann, M. Bauer, U. Settmacher, K. Hekmat, C.S. Hartog. "Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: A prospective sequential comparison".
    Crit Care Med 2011 Jun; 39(6):1335-42.
  29. M. Kohl and H.P. Deigner.
    "Preprocessing of gene expression data by optimally robust estimator".
    BMC Bioinformatics 2010, 11:583. Highly accessed
  30. M. Kohl and P. Ruckdeschel (both authors contributed equally).
    "R Package distrMod: S4 Classes and Methods for Probability Models".
    Journal of Statistical Software 2010, 35(10), 1-27.
  31. Y. Sakr, J. Marques, S. Mortsch, M.D. Gonsalves, K. Hekmat, B. Kabisch, M. Kohl, K. Reinhart.
    "Is the SAPS II score valid in surgical intensive care unit patients?".
    Eval Clin Pract 2012 Apr; 18(2):231-7.
  32. S. Perz, T. Uhlig, M. Kohl, D.L. Bredle, K. Reinhart, M. Bauer, A. Kortgen
    "Low and "supranormal" central venous oxygen saturation and markers of tissue hypoxia in cardiac surgery patients: a prospective observational study".
    Intensive Care Med 2011 Jan; 37(1):52-9.
  33. D. Gräßel, T.M. Ringer, C. Fitzek, S. Fitzek, M. Kohl, W.A. Kaiser, O.W. Witte, H. Axer
    "Wallerian Degeneration of Pyramidal Tract after Paramedian Pons Infarct".
    Cerebrovasc Dis. 2010 Aug 5;30(4):380-388.
  34. M. Kohl, P. Ruckdeschel, and H. Rieder.
    "Infinitesimally Robust Estimation in General Smoothly Parametrized Models".
    Statistical Methods and Application 2010, 19(3):333–354.
  35. MAQC Consortium, Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ, Su Z, Chu TM, Goodsaid FM, Pusztai L, Shaughnessy JD Jr, Oberthuer A, Thomas RS, Paules RS, Fielden M, Barlogie B, Chen W, Du P, Fischer M, Furlanello C, Gallas BD, Ge X, Megherbi DB, Symmans WF, Wang MD, Zhang J, Bitter H, Brors B, Bushel PR, Bylesjo M, Chen M, Cheng J, Cheng J, Chou J, Davison TS, Delorenzi M, Deng Y, Devanarayan V, Dix DJ, Dopazo J, Dorff KC, Elloumi F, Fan J, Fan S, Fan X, Fang H, Gonzaludo N, Hess KR, Hong H, Huan J, Irizarry RA, Judson R, Juraeva D, Lababidi S, Lambert CG, Li L, Li Y, Li Z, Lin SM, Liu G, Lobenhofer EK, Luo J, Luo W, McCall MN, Nikolsky Y, Pennello GA, Perkins RG, Philip R, Popovici V, Price ND, Qian F, Scherer A, Shi T, Shi W, Sung J, Thierry-Mieg D, Thierry-Mieg J, Thodima V, Trygg J, Vishnuvajjala L, Wang SJ, Wu J, Wu Y, Xie Q, Yousef WA, Zhang L, Zhang X, Zhong S, Zhou Y, Zhu S, Arasappan D, Bao W, Lucas AB, Berthold F, Brennan RJ, Buness A, Catalano JG, Chang C, Chen R, Cheng Y, Cui J, Czika W, Demichelis F, Deng X, Dosymbekov D, Eils R, Feng Y, Fostel J, Fulmer-Smentek S, Fuscoe JC, Gatto L, Ge W, Goldstein DR, Guo L, Halbert DN, Han J, Harris SC, Hatzis C, Herman D, Huang J, Jensen RV, Jiang R, Johnson CD, Jurman G, Kahlert Y, Khuder SA, Kohl M, Li J, Li L, Li M, Li QZ, Li S, Li Z, Liu J, Liu Y, Liu Z, Meng L, Madera M, Martinez-Murillo F, Medina I, Meehan J, Miclaus K, Moffitt RA, Montaner D, Mukherjee P, Mulligan GJ, Neville P, Nikolskaya T, Ning B, Page GP, Parker J, Parry RM, Peng X, Peterson RL, Phan JH, Quanz B, Ren Y, Riccadonna S, Roter AH, Samuelson FW, Schumacher MM, Shambaugh JD, Shi Q, Shippy R, Si S, Smalter A, Sotiriou C, Soukup M, Staedtler F, Steiner G, Stokes TH, Sun Q, Tan PY, Tang R, Tezak Z, Thorn B, Tsyganova M, Turpaz Y, Vega SC, Visintainer R, von Frese J, Wang C, Wang E, Wang J, Wang W, Westermann F, Willey JC, Woods M, Wu S, Xiao N, Xu J, Xu L, Yang L, Zeng X, Zhang J, Zhang L, Zhang M, Zhao C, Puri RK, Scherf U, Tong W, Wolfinger RD.
    "The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models".
    Nat Biotechnol. 2010 Aug;28(8):827-38.
  36. U. Kern, M. Kohl, R.T. Kiefer.
    "Lidocaine patch for therapy of neuropathic and non-neuropathic pain : A clinical case series of 87 patients".
    [Article in German]
    Nervenarzt. 2010 Dec; 81(12):1490-1497.
  37. W. Griffith, T. Koal, Y. Wang, M. Kohl, D.P. Enot, H.P. Deigner.
    "Targeted Metabolomics For Biomarker Discovery".
    German Version. Angewandte Chemie 2010, 49(32):5426-5445.
  38. M.W. Sieber, M. Guenther, M. Kohl, O.W. Witte, R.A. Claus, and C. Frahm.
    "Inter-age consistency in bona fide unvaried transcripts".
    Neurobiol Aging. 2010 Apr; 31(4):654-64.
  39. M. Kohl.
    "Development and validation of predictive molecular signatures".
    Curr Mol Med. 2010 Mar; 10(2):173-9.
  40. J.B.P. Landré, M.F. Blaess, M. Kohl, T. Schlicksbier, A. Ruryk, R. Kinscherf, R.A. Claus, A. Hermetter, M. Keller, M. Bauer, H.P. Deigner.
    "Addressable Bipartite Molecular Hook (ABMH): Immobilized Hairpin Probes with Sensitivity below 50 Femtomolar".
    Analytical Biochemistry 2010 Feb 1; 397(1):60-6.
  41. J. Winning, J. Neumann, M. Kohl, R.A. Claus, K. Reinhart, M. Bauer, W. Lösche.
    "Antiplatelet drugs and outcome in mixed admissions to an intensive care unit*".
    Crit Care Med 2010 Jan; 38(1):32-7.
  42. U. Kern, V. Busch, M. Rockland, M. Kohl, and F. Birklein.
    "Prevalence and risk factors of phantom limb pain and phantom limb sensations in Germany: A nationwide field survey".
    [Article in German]
    Schmerz 2009 Oct; 23(5):479-88.
  43. H.P. Deigner and M. Kohl.
    "The molecular sepsis signature".
    Crit Care Med 2009 Mar; 37(3):1137-8.
  44. J. Winning, J. Reichel, Y. Eisenhut, J. Hamacher, M. Kohl, H.P. Deigner, R.A. Claus, M. Bauer, and W. Lösche.
    "Anti-platelet drugs and outcome in severe infection: Clinical impact and underlying mechanisms".
    Platelet 2009 Feb; 20(1):50-7.
  45. H. Rieder, M. Kohl, and P. Ruckdeschel.
    "The Costs of not Knowing the Radius".
    Statistical Methods and Application 2008, 17(1):13-40.
    Download as .pdf-File [as submitted; (486 KB)] or as [extended version; (969 KB)].
  46. U. Kern, B. Altkemper, and M. Kohl.
    "Management of phantom pain with a textile, electromagnetically acting stump liner. A randomized double-blind crossover study".
    Journal of Pain and Symptom Management 2006 Oct, 32(4):352-360.
  47. P. Ruckdeschel, M. Kohl, T. Stabla and F. Camphausen.
    "S4 Classes for Distributions".
    R-News 2006 May, 6(2):2-6.


  1. N. Horbenko, M. Kohl, D. Pupashenko, M. Pupashenko and P. Ruckdeschel.
    R-Package "distrRmetrics: Package distr classes for distributions from Rmetrics".
    CRAN since 02/2013.
  2. J. Perkins, M. Kohl.
    Bioconductor-Package "NormqPCR: Functions for normalisation of RT-qPCR data".
    Bioconductor since 07/2011.
  3. J. Perkins, M. Kohl.
    Bioconductor-Package "ReadqPCR: Read qPCR data".
    Bioconductor since 07/2011.
  4. F. Flessa, A. Kehl and M. Kohl.
    R-Package "RFLPtools: Tools to analyse RFLP data".
    CRAN since 02/2010.
  5. M. Kohl.
    R-Package "RobLoxBioC: Infinitesimally robust estimators for preprocessing omics data".
    CRAN since 11/2009.
  6. M. Kohl and P. Ruckdeschel.
    R-Package "RobAStBase: Robust Asymptotic Statistics".
    CRAN since 09/2008.
  7. P. Ruckdeschel and M. Kohl.
    R-Package "distrMod: Object orientated implementation of probability models".
    CRAN since 09/2008.
  8. P. Ruckdeschel, M. Kohl, A. Hueller and E. Feist.
    R-Package "distrTeach: Extensions of package distr for teaching Stochastics/Statistics in secondary school".
    CRAN since 09/2008.
  9. M. Kohl.
    R-Package "MKmisc: Miscellaneous Functions from M. Kohl ".
    CRAN since 09/2008.
  10. M. Kohl.
    R-Package "RobRex: Optimally robust influence curves for regression and scale".
    CRAN since 08/2007.
  11. M. Kohl and P. Ruckdeschel.
    R-Package "ROptRegTS: Optimally robust estimation for regression-type models".
    CRAN since 08/2007.
  12. M. Kohl.
    R-Package "RobLox: Optimally robust influence curves for location and scale".
    CRAN since 08/2007.
  13. M. Kohl and P. Ruckdeschel.
    R-Package "ROptEst: Optimally robust estimation using S4 classes and methods".
    CRAN since 08/2007.
  14. M. Kohl.
    Bioconductor-Package "SLqPCR: Functions for analysis of real-time quantitative PCR data at SIRS-Lab GmbH".
    Bioconductor since 01/2007.
  15. M. Kohl.
    R-Package "SLmisc: Miscellaneous Functions for analysis of gene expression data at SIRS-Lab GmbH".
    CRAN from 01/2007 to 08/2009 (now CRAN archive).
  16. P. Ruckdeschel, M. Kohl, T. Stabla, and F. Camphausen.
    R-Package "distrDoc: Documentation for packages distr, distrEx, distrSim, distrTEst, distrTeach, and distrMod".
    CRAN since 11/2006.
  17. M. Kohl and P. Ruckdeschel.
    R-Package "RandVar: Implementation of random variables".
    CRAN since 10/2005.
  18. M. Kohl and P. Ruckdeschel.
    R-Package "distrEx: Extensions of package distr".
    CRAN since 10/2005.
  19. P. Ruckdeschel, M. Kohl, T. Stabla, and F. Camphausen.
    R-Package "distrTEst: Estimation and Testing classes based on package distr".
    CRAN since 10/2005.
  20. P. Ruckdeschel, M. Kohl, T. Stabla, and F. Camphausen.
    R-Package "distrSim: Simulation classes based on package distr".
    CRAN since 10/2005.
  21. P. Ruckdeschel, M. Kohl, T. Stabla, and F. Camphausen.
    R-Package "distr: Object orientated implementation of distributions".
    CRAN since 04/2004.

Development Versions

Unpublished Manuscripts/Technical Reports

  1. M. Kohl.
    "Asymptotic Theory of Robustness - a short summary".
    Technical Report 2005, University of Bayreuth.
  2. M. Kohl.
    "Installation und erste Schritte mit R".
    Technical Report 2011, Furtwangen University.
  3. P. Ruckdeschel and M. Kohl.
    "R/S-Plus für Einsteiger und Fortgeschrittene".
    Slides, University of Bayreuth.
  4. P. Ruckdeschel and M. Kohl.
    "Computation of the Finite Sample Risk of M-estimators on Neighborhoods".
    Unpublished manuscript.